Carl W White Selected Research

AEOL 10150

12/2016	From the Cover: Catalytic Antioxidant Rescue of Inhaled Sulfur Mustard Toxicity.
7/2014	Catalytic antioxidant AEOL 10150 treatment ameliorates sulfur mustard analog 2-chloroethyl ethyl sulfide-associated cutaneous toxic effects.
3/2011	AEOL10150: a novel therapeutic for rescue treatment after toxic gas lung injury.
5/2010	Treatment with the catalytic metalloporphyrin AEOL 10150 reduces inflammation and oxidative stress due to inhalation of the sulfur mustard analog 2-chloroethyl ethyl sulfide.

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Carl W White Research Topics

Disease

20	Hypoxia (Hypoxemia) 01/2022 - 09/2002
15	Inflammation (Inflammations) 02/2024 - 05/2007
11	Wounds and Injuries (Trauma) 05/2015 - 04/2011
9	Airway Obstruction (Choking) 01/2024 - 12/2010
9	Respiratory Insufficiency (Respiratory Failure) 01/2022 - 04/2004
8	Hyperoxia 01/2022 - 09/2002
6	Lung Injury 02/2024 - 04/2006
6	Cystic Fibrosis (Mucoviscidosis) 02/2012 - 05/2004
5	Acute Lung Injury 01/2022 - 01/2012
4	Asthma (Bronchial Asthma) 01/2020 - 07/2010
3	Fibrosis (Cirrhosis) 02/2024 - 01/2018
3	Prostatic Hyperplasia (Benign Prostatic Hyperplasia) 12/2013 - 11/2010
3	Bronchopulmonary Dysplasia 06/2007 - 02/2004
2	Pathologic Constriction (Stenosis) 02/2024 - 06/2007
2	Poisoning 05/2022 - 01/2021
2	Pulmonary Hypertension 10/2020 - 07/2013
2	Airway Remodeling 01/2020 - 01/2017
2	Ataxia (Dyssynergia) 01/2018 - 06/2010
2	Bronchiolitis Obliterans 01/2018 - 01/2017
2	Bronchitis 02/2015 - 04/2013
2	Edema (Dropsy) 03/2014 - 03/2009
2	Vascular Remodeling 07/2013 - 12/2005
2	Respiratory Hypersensitivity 03/2011 - 10/2010
2	Mitochondrial Diseases (Mitochondrial Disease) 01/2011 - 03/2009
2	Lung Diseases (Lung Disease) 01/2011 - 02/2004
2	Necrosis 06/2010 - 07/2002
2	Premature Birth (Birth, Premature) 06/2007 - 12/2005
1	Pneumonia (Pneumonitis) 02/2024
1	Neoplasms (Cancer) 01/2022
1	Acidosis 11/2020
1	Chorioamnionitis 10/2020
1	Hypertrophy 10/2020
1	Chronic Obstructive Pulmonary Disease (COPD) 01/2020
1	Hemangioma (Angioma) 01/2019
1	Lower Urinary Tract Symptoms 01/2019
1	Breast Neoplasms (Breast Cancer) 01/2019

Drug/Important Bio-Agent (IBA)

23	Mustard Gas (Sulfur Mustard)IBA 02/2024 - 05/2010
14	2-chloroethyl ethyl sulfideIBA 02/2015 - 03/2009
10	Oxygen (Dioxygen)IBA 01/2024 - 02/2003
8	Proteins (Proteins, Gene)FDA Link 01/2022 - 02/2004
8	AntioxidantsIBA 12/2016 - 02/2004
6	FibrinIBA 11/2020 - 04/2013
6	Irritants (Vesicants)IBA 02/2015 - 07/2010
5	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 11/2022 - 04/2005
4	ThioredoxinsIBA 01/2022 - 05/2004
4	Tissue Plasminogen Activator (Alteplase)FDA Link 11/2020 - 04/2013
4	OzoneIBA 01/2020 - 07/2010
4	ChlorineIBA 01/2018 - 07/2010
4	Biomarkers (Surrogate Marker)IBA 12/2016 - 10/2010
4	AEOL 10150IBA 12/2016 - 05/2010
4	Mechlorethamine (Nitrogen Mustard)FDA Link 05/2015 - 01/2013
4	Prolyl Hydroxylases (Prolyl Hydroxylase)IBA 06/2007 - 04/2005
3	CytokinesIBA 02/2024 - 05/2007
3	AntidotesIBA 01/2024 - 05/2015
3	Adrenergic Receptors (Adrenergic Receptor)IBA 01/2019 - 04/2012
3	Chemical Warfare AgentsIBA 01/2017 - 01/2012
3	Oxidants (Oxidizing Agents)IBA 06/2014 - 02/2004
3	Transcription Factors (Transcription Factor)IBA 07/2013 - 11/2002
3	CalciumIBA 01/2011 - 06/2007
3	Adenosine Triphosphate (ATP)IBA 12/2005 - 11/2002
2	SodiumIBA 01/2024 - 01/2022
2	cobinamideIBA 05/2022 - 01/2021
2	Sulfhydryl Compounds (Thiols)IBA 01/2022 - 01/2021
2	CollagenIBA 01/2017 - 03/2014
2	Silybin (Lagosa)IBA 05/2015 - 01/2012
2	PlasticsIBA 02/2015 - 04/2013
2	Adrenergic Agents (Adrenergic Drugs)IBA 12/2013 - 01/2013
2	Phosphotransferases (Kinase)IBA 09/2011 - 06/2010
2	Methionine (L-Methionine)FDA Link 03/2009 - 01/2006
2	Reactive Oxygen Species (Oxygen Radicals)IBA 03/2009 - 03/2006
2	DNA (Deoxyribonucleic Acid)IBA 03/2009 - 11/2002
2	Glucose (Dextrose)FDA LinkGeneric 04/2006 - 09/2002
2	Apyrase (ATP Diphosphatase)IBA 04/2004 - 11/2002
1	ReninIBA 11/2022
1	Nicotine FDA Link 11/2022
1	Thromboplastin (Tissue Factor)IBA 11/2022
1	AngiotensinsIBA 11/2022
1	Transforming Growth Factors (Transforming Growth Factor)IBA 11/2022
1	Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)IBA 11/2022
1	Vitamin B 12 (Cyanocobalamin)FDA LinkGeneric 05/2022
1	Acrolein (Aqualin)IBA 01/2022
1	Cyclophosphamide (Cytoxan)FDA LinkGeneric 01/2022
1	Mesna (Coenzyme M)FDA LinkGeneric 01/2022
1	p38 Mitogen-Activated Protein KinasesIBA 01/2022
1	Superoxides (Superoxide)IBA 01/2022
1	Peroxisome Proliferator-Activated Receptors (PPAR)IBA 01/2022
1	Messenger RNA (mRNA)IBA 01/2022
1	Uncoupling Protein 2IBA 01/2022
1	methyl isocyanateIBA 11/2020
1	Prolyl-Hydroxylase InhibitorsIBA 10/2020
1	Nitrogen DioxideIBA 01/2020
1	Air Pollutants (Pollutants, Air)IBA 01/2020
1	Particulate MatterIBA 01/2020
1	SootIBA 01/2020
1	PlacebosIBA 05/2019
1	Propranolol (Inderal)FDA LinkGeneric 01/2019

Therapy/Procedure

9	Therapeutics 10/2020 - 02/2004
2	Artificial Respiration (Mechanical Ventilation) 06/2007 - 02/2004
1	Ligation 02/2024
1	Critical Care (Surgical Intensive Care) 01/2022